Condition Strategy

Low Testosterone and Andropause

Restore testosterone to functional range, preserve muscle mass and cognitive vitality

Evidence Level B

Evidence and Risk Labels

Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.

See full scoring guide

Guidance Summary

Testosterone declines ~1% per year after age 30 in men. Lifestyle interventions — particularly resistance training, sleep, and correcting nutrient deficiencies (zinc, vitamin D) — are first-line. Ashwagandha and fenugreek show modest RCT support. TRT is indicated when levels fall below clinical thresholds with symptoms.

Top Interventions

  • progressive resistance training
  • sleep optimization (7-9 hours)
  • body fat reduction
  • zinc and vitamin D optimization
  • stress reduction

Monitoring Priorities

  • total testosterone (morning draw)
  • free testosterone
  • SHBG
  • LH and FSH
  • hematocrit (if on TRT)
  • PSA (if on TRT)

Source Links