Adaptogen for stress and fatigue

Eleuthero (Siberian Ginseng)

Eleuthero (Eleutherococcus senticosus) is an adaptogen with evidence in animal and some human studies for stress resilience and fatigue reduction. Evidence quality is lower than for rhodiola or ashwagandha.

Evidence Level C

Evidence and Risk Labels

Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.

See full scoring guide

Clinical Snapshot

Effect Size
Modest improvements in fatigue and stress indices in small trials; effect sizes generally below rhodiola
Safety
Low Risk

May interact with digoxin (pharmacokinetic interference); avoid in hypertension without monitoring.

Research Dosing

This reflects common ranges and protocols used in published studies, not personal medical advice.

Typical Daily Dose
400-800 mg (standardized extract)
Timing
Morning with meals
Protocol Duration in Studies
8-12 weeks, with cycling

Standardized to eleutherosides for consistency; quality varies significantly by brand.

Best Fit Profiles

  • mild stress and fatigue support as part of broader adaptogen protocol

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