2026-02-24
Kidney Health and Aging: GFR Decline, Protein Intake, and Renoprotective Strategies
GFR declines ~1 mL/min/year after age 40. In early-stage CKD, protein restriction, blood pressure control, and avoiding nephrotoxic supplements (high-dose oxalate, aristolochic acid) are the primary levers. Potassium citrate and omega-3 have supportive evidence.
2026-02-24
Menopause and Perimenopause: Supplement Evidence for Hot Flashes, Bone Loss, and Cognitive Symptoms
The menopausal transition accelerates bone loss, cognitive change, sleep disruption, and cardiovascular risk. Supplement evidence varies sharply: isoflavones have modest hot flash data; calcium and vitamin D are well-supported for bone; magnesium helps sleep. Black cohosh is used widely but evidence is mixed.
2026-02-24
Sodium-Potassium Balance in Aging: The Dietary Lever for Blood Pressure and Vascular Health
The ratio of dietary sodium to potassium is a more powerful predictor of cardiovascular risk than sodium intake alone. This article reviews the evidence for the Na/K balance as a therapeutic target and practical approaches to correction.
2026-02-24
Zone 2 Training and Mitochondrial Health: Evidence for Endurance, Metabolic, and Longevity Benefits
Zone 2 training — sustained low-intensity aerobic work — is the primary stimulus for mitochondrial biogenesis and fat oxidation capacity. This review covers how to define and perform zone 2, the evidence for its health and longevity benefits, and how it fits into a complete training program.
2026-02-23
Blood Sugar and Insulin Resistance: Supplement Protocol, Monitoring, and Evidence Summary
Insulin resistance precedes type 2 diabetes by years and independently drives cardiovascular risk, cognitive decline, and accelerated aging. Berberine, magnesium, alpha-lipoic acid, and chromium have the best evidence among supplements. This protocol integrates the strongest interventions with clear monitoring markers.