2026-02-24
Chronic Allergic Inflammation in Aging: Mechanisms and Evidence-Based Management
Allergic inflammation can worsen with immune senescence, contributing to systemic inflammatory load. This article covers the evidence for dietary and supplement interventions that modulate allergic response without the side effects of antihistamines.
2026-02-24
Gut Barrier Integrity in Aging: Intestinal Permeability, Inflammaging, and Support
Age-related increases in intestinal permeability ("leaky gut") allow bacterial products including lipopolysaccharide (LPS) to enter systemic circulation, driving chronic low-grade inflammation associated with multiple aging-related conditions. Evidence-based interventions include dietary fiber, fermented foods, and specific probiotics — though research on reversing permeability changes in older humans is in early stages.
2026-02-24
Recurrent UTIs in Aging: Prevention Strategies Beyond Antibiotics
Recurrent urinary tract infections are common in older adults, particularly post-menopausal women, and lead to significant antibiotic overuse. This article covers evidence-based prevention strategies including d-mannose, cranberry, and vaginal microbiome support.
2026-02-21
Gut Microbiome and Probiotics in Aging: Diversity Decline, Leaky Gut, and Evidence-Based Interventions
The gut microbiome undergoes progressive diversity loss with age — a pattern linked to increased intestinal permeability, systemic inflammation, and reduced short-chain fatty acid production. Dietary fiber, fermented foods, and targeted probiotics have the best evidence for reversing these changes.
2026-02-21
Lactobacillus acidophilus: Gut Health, Immune Modulation, and Strain-Specific Evidence
Lactobacillus acidophilus is one of the most studied probiotic species, with evidence spanning IBS symptom relief, immune modulation, and cholesterol reduction. Strain specificity matters enormously — not all L. acidophilus products produce identical effects.