Feb 10, 2026Drug-Supplement Interactions: Warfarin, Statins, Metformin, and SSRIs — Common ConcernsMany commonly used supplements interact with medications — some significantly. Vitamin K interacts with warfarin. CoQ10 may modulate statin effects. Fish oil affects bleeding risk. NAC interacts with nitroglycerin. This guide maps the most clinically relevant interactions for the common longevity supplement stack.