Feb 24, 2026Estrogen, Menopause, and Aging: Hormonal Mechanisms, Health Implications, and ProtocolMenopause-associated estrogen decline drives accelerated changes in cardiovascular risk, bone density, cognitive function, and metabolic health. Menopausal hormone therapy (MHT) has RCT and observational evidence supporting benefits for symptomatic relief and bone protection; cardiovascular and breast cancer risks depend on timing, type, and route of administration.
Feb 24, 2026Menopause and Perimenopause: Supplement Evidence for Hot Flashes, Bone Loss, and Cognitive SymptomsThe menopausal transition accelerates bone loss, cognitive change, sleep disruption, and cardiovascular risk. Supplement evidence varies sharply: isoflavones have modest hot flash data; calcium and vitamin D are well-supported for bone; magnesium helps sleep. Black cohosh is used widely but evidence is mixed.
Feb 21, 2026Longevity Protocol for Women Over 50: Evidence-Based PrioritiesPerimenopause and post-menopause mark a major metabolic and hormonal inflection point. This protocol covers the highest-leverage interventions for women over 50, grounded in current evidence.