Feb 24, 2026GLP-1 Agonists and Aging: Metabolic Benefits, Cardiovascular Evidence, and Longevity ImplicationsGLP-1 receptor agonists like semaglutide have demonstrated cardiovascular and metabolic benefits beyond weight reduction. This review covers the mechanistic basis, major trial evidence, and the open questions about their role in longevity medicine.
Feb 24, 2026Zone 2 Training and Mitochondrial Health: Evidence for Endurance, Metabolic, and Longevity BenefitsZone 2 training — sustained low-intensity aerobic work — is the primary stimulus for mitochondrial biogenesis and fat oxidation capacity. This review covers how to define and perform zone 2, the evidence for its health and longevity benefits, and how it fits into a complete training program.