Jan 25, 2026Acetyl-L-Carnitine (ALCAR) and Brain Aging: Evidence, Mechanism, and Nerve HealthAcetyl-L-carnitine (ALCAR) crosses the blood-brain barrier and supports acetylcholine synthesis and mitochondrial function in neurons. Evidence supports mild cognitive decline and peripheral neuropathy. ALCAR differs importantly from L-carnitine in CNS access.
Jan 10, 2026Alpha-Lipoic Acid: Metabolic Health, Peripheral Neuropathy, and R-ALA vs Racemic FormsAlpha-lipoic acid has the strongest evidence base in peripheral neuropathy (including diabetic neuropathy) where IV and high-dose oral formulations show consistent benefit. Metabolic effects are real but smaller.