Feb 18, 2026Vitamin D3 and Telomere Attrition: Findings from the VITAL Randomized TrialA VITAL sub-study (n=1,054, 4 years, 2,000 IU/day vitamin D3) found reduced leukocyte telomere attrition in the vitamin D group versus placebo. Omega-3 showed no significant effect. Telomere length is a surrogate marker; clinical outcome implications are uncertain.