2026-02-22
Anemia and Iron Deficiency in Aging: Diagnosis, Causes, and Supplementation Evidence
Anemia affects 10–20% of adults over 65 and is independently associated with frailty, cognitive decline, and mortality. Iron deficiency is the most common cause but is often missed in older adults. Supplementation restores function when deficiency is confirmed — but iron excess is harmful and routine supplementation without deficiency is not indicated.
2026-02-20
Thyroid Function Variability: Selenium, Zinc, and Myo-Inositol in Clinical Context
Thyroid symptom variability should be managed by medication and lab stability first. Selenium, zinc, and myo-inositol may be adjuncts in selected contexts, not primary treatment.
2026-02-18
CoQ10 and Mitochondrial Function: Age-Related Decline and Clinical Evidence
CoQ10 declines with age and statin exposure. Human evidence is strongest in heart failure and statin-associated muscle symptoms, while prevention use in healthy adults remains less certain.
2026-02-17
NAD+ Precursor Supplementation and Cognitive Fatigue: Mechanism and Human Evidence
NAD+ precursors reliably elevate blood NAD+ in humans and activate mitochondrial energy pathways. Whether this translates to clinically meaningful reductions in cognitive fatigue requires larger, longer trials.