2026-02-24
Muscle Power in Aging: Why Force Speed Matters More Than Strength Alone
Muscle power — the ability to generate force quickly — declines faster than strength with aging and is a stronger predictor of functional independence and fall risk. This article covers the evidence for power-oriented training and nutritional support.
2026-02-24
Post-Hospitalization Recovery: Reversing Deconditioning and Preventing Long-Term Frailty
Hospitalization is a major driver of functional decline in older adults. Even short stays cause substantial muscle loss and reduce independence. This article covers the evidence for rapid, structured recovery with early mobilization and targeted nutritional support.
2026-02-20
Creatine for Aging: Muscle Preservation, Cognitive Benefits, and Monohydrate vs Alternatives
Creatine monohydrate is one of the most evidence-backed supplements for older adults, improving muscle strength, power output, and lean mass when combined with resistance training. Emerging evidence supports cognitive benefits — particularly working memory and processing speed. Monohydrate remains superior to proprietary alternatives.
2026-02-18
Rapamycin in Older Adults: PEARL Trial Findings on Dose, Sex Differences, and Body Composition
The PEARL trial tested low-dose weekly rapamycin in healthy older adults. The primary endpoint — visceral fat reduction — was not met. Secondary analyses suggested lean tissue effects at higher doses in women, but these require confirmation in adequately powered trials.
2026-02-18
POLYCAD Trial: Spermidine Supplementation in Coronary Artery Disease — Design and Interim Context
The POLYCAD trial is testing 24 mg/day spermidine in 187 older adults with coronary artery disease for 48 weeks. Trial completion is expected August 2026 — no efficacy results exist yet. Prior cohort data from Eisenberg et al. 2016 provides the rationale.