2026-02-19
Lion's Mane and Cognitive Function: Mechanisms, Human Evidence, and Protocol
Lion's Mane mushroom stimulates nerve growth factor production and has shown cognitive benefits in small randomized trials in older adults, with preclinical evidence stronger than human data.
2026-02-19
Resveratrol and Memory Retention: Evidence from a 26-Week Randomized Trial in Older Adults
Witte et al. (2014) found statistically significant memory improvements in adults 50–75 taking 200 mg/day resveratrol for 26 weeks, alongside improved hippocampal connectivity and glucose metabolism. Sample size was small (n=46) and findings require replication.
2026-02-17
Alzheimer's and Dementia Prevention: What the Evidence Says
Cognitive decline is not inevitable. This protocol reviews the strongest modifiable risk factors and evidence-based interventions for reducing Alzheimer's and dementia risk.
2026-02-03
Cognitive Enhancement Stacks: Lion's Mane vs Bacopa vs Citicoline vs PS vs ALCAR — Evidence Comparison
Five well-studied cognitive supplements work through distinct mechanisms. This article compares evidence quality, time-to-effect, practical considerations, and optimal combinations for lion's mane (NGF), bacopa (memory consolidation), citicoline (choline), phosphatidylserine (membrane), and acetyl-L-carnitine (mitochondrial).
2026-02-03
Magnesium L-Threonate and Brain Health: Evidence from Human Trials
Magnesium L-threonate was developed to improve brain magnesium delivery. Human trials show modest cognitive improvements in older adults, though sample sizes are small and independent replication is limited.