Best Fit Profiles
- liver health support and choline delivery for cognitive and membrane protocols
Cell membrane integrity and liver health
Phosphatidylcholine
Phosphatidylcholine is the primary phospholipid in cell membranes and a choline source. RCTs support its use in non-alcoholic fatty liver disease and liver enzyme normalization. Also serves as a choline source for acetylcholine synthesis.
Evidence Level B
Evidence and Risk Labels
Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.
See full scoring guideClinical Snapshot
- Effect Size
- Meaningful liver enzyme reduction in NAFLD; moderate cognitive choline support
- Safety
- Low Risk
TMAO conversion from choline in gut bacteria is debated as a cardiovascular risk factor; current evidence does not support restricting food-based choline.
Research Dosing
This reflects common ranges and protocols used in published studies, not personal medical advice.
- Typical Daily Dose
- 1000-3000 mg
- Timing
- With meals
- Protocol Duration in Studies
- 12-16 weeks for liver endpoints
Sunflower lecithin is a common source; phosphatidylcholine content varies by preparation.