2026-02-24
Senolytics and Cellular Senescence: Mechanisms, Mayo Clinic Evidence, and Clinical Status
Senolytics are drugs and compounds that selectively clear senescent cells, which accumulate with age and drive chronic inflammation. This review covers the mechanisms, the Mayo Clinic dasatinib+quercetin trials, fisetin evidence, and the current clinical status.
2026-02-24
Air Pollution, Oxidative Stress, and Nutritional Protection
Air pollution is a top-5 global health risk. While environmental mitigation is primary, nutritional strategies can blunt some of the inflammatory and oxidative damage from particulate and ozone exposure.
2026-02-24
Alcohol, Aging, and Long-Term Health: What the Evidence Shows
Alcohol consumption interacts with aging biology in complex ways. This article covers the liver, brain, cardiovascular, and cancer evidence, plus what nutritional strategies can mitigate harm.
2026-02-24
Chronic Allergic Inflammation in Aging: Mechanisms and Evidence-Based Management
Allergic inflammation can worsen with immune senescence, contributing to systemic inflammatory load. This article covers the evidence for dietary and supplement interventions that modulate allergic response without the side effects of antihistamines.
2026-02-24
Exercise Recovery in Aging: Why Recovery Slows and Evidence-Based Strategies
Recovery from exercise slows significantly with age, affecting how often and how hard older adults can train. This review covers the biological reasons for prolonged recovery, its consequences for muscle preservation, and evidence-based strategies to support faster, more complete recovery.