2026-02-24
Blue Zone Dietary Patterns: What the Longest-Lived Populations Actually Eat
Blue Zone populations (Sardinia, Okinawa, Nicoya, Ikaria, Loma Linda) share dietary patterns centered on whole plant foods, moderate caloric density, and minimal ultra-processed food. Epidemiological data consistently associates these patterns with lower all-cause mortality, though confounding by lifestyle, social, and genetic factors limits causal inference.
2026-02-24
Polyphenol Stack Synergy: Quercetin, Resveratrol, Curcumin, and EGCG Combined Evidence
Quercetin, resveratrol, curcumin, and EGCG activate overlapping pathways — NRF2, SIRT1, AMPK, and NFkB inhibition. Stacking them is popular but evidence for synergistic human benefit is largely extrapolated from in vitro and animal models. This article assesses what stacking adds and what it does not.
2026-02-24
Sodium-Potassium Balance in Aging: The Dietary Lever for Blood Pressure and Vascular Health
The ratio of dietary sodium to potassium is a more powerful predictor of cardiovascular risk than sodium intake alone. This article reviews the evidence for the Na/K balance as a therapeutic target and practical approaches to correction.
2026-02-21
Gut Microbiome and Probiotics in Aging: Diversity Decline, Leaky Gut, and Evidence-Based Interventions
The gut microbiome undergoes progressive diversity loss with age — a pattern linked to increased intestinal permeability, systemic inflammation, and reduced short-chain fatty acid production. Dietary fiber, fermented foods, and targeted probiotics have the best evidence for reversing these changes.
2026-02-20
Arterial Stiffness Risk: Cocoa Flavanols, Aged Garlic, Olive Leaf, and Beetroot
Aerobic training and blood-pressure control remain primary for arterial stiffness. Cocoa flavanols, aged garlic, olive leaf, and beetroot may provide modest vascular support.