2026-02-24
Alcohol, Aging, and Long-Term Health: What the Evidence Shows
Alcohol consumption interacts with aging biology in complex ways. This article covers the liver, brain, cardiovascular, and cancer evidence, plus what nutritional strategies can mitigate harm.
2026-02-24
Blue Zone Dietary Patterns: What the Longest-Lived Populations Actually Eat
Blue Zone populations (Sardinia, Okinawa, Nicoya, Ikaria, Loma Linda) share dietary patterns centered on whole plant foods, moderate caloric density, and minimal ultra-processed food. Epidemiological data consistently associates these patterns with lower all-cause mortality, though confounding by lifestyle, social, and genetic factors limits causal inference.
2026-02-24
Gut Barrier Integrity in Aging: Intestinal Permeability, Inflammaging, and Support
Age-related increases in intestinal permeability ("leaky gut") allow bacterial products including lipopolysaccharide (LPS) to enter systemic circulation, driving chronic low-grade inflammation associated with multiple aging-related conditions. Evidence-based interventions include dietary fiber, fermented foods, and specific probiotics — though research on reversing permeability changes in older humans is in early stages.
2026-02-24
Age-Related Hearing Loss: Mechanisms, Cognitive Links, and Nutritional Support
Age-related hearing loss (presbycusis) affects over 60% of adults over 70 and independently accelerates cognitive decline. This article reviews the mechanisms and the limited but growing evidence base for nutritional support.
2026-02-24
Menopause and Perimenopause: Supplement Evidence for Hot Flashes, Bone Loss, and Cognitive Symptoms
The menopausal transition accelerates bone loss, cognitive change, sleep disruption, and cardiovascular risk. Supplement evidence varies sharply: isoflavones have modest hot flash data; calcium and vitamin D are well-supported for bone; magnesium helps sleep. Black cohosh is used widely but evidence is mixed.